General information

Course type AMUPIE
Module title Principles Of Medical Virology
Language English
Module lecturer prof. UAM dr hab. Julia Łucja Durzyńska, prof. UAM dr hab. Robert Nawrot, dr hab. Justyna Broniarczyk
Lecturer's email
Lecturer position profesor uczelni (associate professor)
Faculty Faculty of Biology
Semester 2024/2025 (summer)
Duration 30


Lectures - March/April 2025

Lab classes - May/June 2025

Module aim (aims)

Pre-requisites in terms of knowledge, skills and social competences (where relevant)

Students should be familiar with the structure and biochemistry of eukaryotic (human) cells.



Week 1: The properties of virus particles (capsid symmetry and virus architecture, virus receptors, recognition, and binding).

Week 2: The structure and complexity of virus genomes (replication strategies, expression processing of viral or cellular pre-mRNA, RNA interference, epigenetics, the diversity of viral translation strategies, packing of the viral genome, virion maturation, release, and spread of virion).

Week 3: Virus-related diseases. Viral pathogenesis (infection of populations, viral virulence, cellular defenses, viruses, and apoptosis).

Week 4: Patterns of infection (acute infections, persistent infections, latent infections, abortive infections, transforming infections).

Week 5: Transformation and oncogenesis.

Week 6: Prevention and therapy of virus infection (vaccines and antiviral agents)

Week 7: Viruses and the future (new and emergent viruses, zoonoses, bioterrorism, virotherapy, viruses for gene delivery, viruses and nanotechnology, viruses and biosphere).


Week 1: Identification of HPV viruses DNA using PCR method.

Week 2: Detection of Epstein-Barr virus using the ELISA assay. Biosafety levels in virology labs.

Week 3: Pseudovirus (PsV) technology as a tool to monitor HPV infection in different cell lines.

Reading list

  1. Fields BN et al.: Fundamental Virology, Lippincott-Raven, Philadelphia-Nwe York, 19952. Dimmock NJ, Primrose SB.: Introduction to Modern Virology, Blackwell Science, Oxford, 19983. Cann AJ: Principles of Molecular Virology, Elsevier, Amsterdam-Boston-London, 20124. Flint SJ et al.: Principles of Virology, ASM Press, Washington, 2009